THE INTERPLAY BETWEEN BIPOLAR DISORDER AND THYROID MALFUNCTIONS: REVIEW ARTICLE

RESUMO

Mohammed Salah Hussein*, Abeer Nasser Al Ghalbi, Abdullah Mohammed Alzahrani, Zabarah Ali Ghaneem, Alwaleed Mohammed Altuwaijri, Waleed Khalid Aljasser, Muteb Khalid Alotaibi, Albaz, Abdullah Moteb A Albaz, Ahmed Hesham Alsahhaf, Abdullah Osama Kentab, Almalki, Zuhair Mofareh B

Bipolar disorder and thyroid dysfunctions often exhibit a complex interplay that can influence the clinical presentation and treatment outcomes for affected individuals. Research indicates that thyroid hormones play a crucial role in mood regulation, and fluctuations in thyroid function can exacerbate or mimic the symptoms of bipolar disorder. For instance, hyperthyroidism, characterized by elevated levels of thyroid hormones, can lead to manic or hypomanic episodes, while hypothyroidism, which involves decreased hormone production, can result in depressive symptoms. This intricate relationship necessitates a comprehensive assessment of thyroid function in patients diagnosed with bipolar disorder to address any potential hormonal imbalances that may worsen mood stability. Moreover, the treatment of bipolar disorder may require careful management of thyroid conditions, as certain mood stabilizers and antidepressants can impact thyroid hormone levels. Medications such as lithium, commonly used to treat bipolar disorder, have been documented to both influence thyroid function and require ongoing monitoring for thyroid-related side effects. Consequently, healthcare providers should conduct thorough evaluations of thyroid function for individuals with bipolar disorder throughout their treatment journey. Effective management strategies should include a collaborative approach involving both psychiatric and endocrinological assessments to optimize overall mental and physical health.