Mansour Hajed Musheh Al-Harthi
Paediatric Resident, Saudi German Hospital-Aseer-paediatric Department, Saudi Arabia
Publications
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Research Article
HOW DOES INSULIN RESISTANCE AFFECT VITAMIN D LEVELS IN OBESE CHILDREN AND ADOLESCENTS
Author(s): Badriah Gharamah Al Asmari*, Najmah Ali Eidah Alotaibi, Abrar Abdullah Ali Alghamdi, Assma Khaled Salwy, Waleed Khallufah Saad Qubayl, Mansour Hajed Musheh Al-Harthi, Asmaa Salah Ghmaird, Walaa Abduraheem Abuharba, Abdulaziz Mashan Almutairi, Khaled Hatem Kariri and Smaher Abdullah Bahawi
Background: Childhood obesity is a growing global concern, often linked to metabolic disorders such as insulin resistance and vitamin D deficiency. Research suggests an inverse relationship between vitamin D levels and insulin resistance, but the underlying mechanisms remain unclear. This study aims to investigate the impact of vitamin D supplementation on insulin resistance in overweight and obese children and adolescents. Methods: This study was conducted on 100 children and adolescents (aged 4–18 years) with a BMI above the 85th percentile and vitamin D deficiency (serum 25-hydroxyvitamin D < 20 ng/ml). Participants received vitamin D supplementation (50,000 IU weekly for 8 weeks, followed by 1,000 IU daily for 3 months). Pre- and postintervention assessments included BMI, fasting blood sugar (FBS), insulin levels, HOMA-IR index,.. Read More»