Wati
Medical Doctor, Wangaya General Hospital, Bali, Indonesia
Publications
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Research Article
CHALLENGING TREATMENT IN MANAGING MAJOR DEPRESSION WITH SUICIDAL IDEATION IN ADOLESCENT PATIENT: A CASE REPORT OF OFF-LABEL ESKETAMINE NASAL SPRAY USAGE
Author(s): Wati*, I Gusti Rai Putra Wiguna, I Putu Belly Sutrisna and Nyoman Widhyalestari Parwatha
Major Depressive Disorder (MDD) is the third most common mental disorder in adolescents. MDD causes diminished quality of life, functional impairment, poor socio-economic outcomes, and increases the risk for suicide. Suicidal ideation is present and appears to be a precondition for suicide attempts in patients with MDD, especially in adolescent patient. Around 1.4% of adolescent patient reported that they had suicidal ideation. This emphasizes the need for treatment options with sustained efficacy and long-term tolerability. In recent years, ketamine has received attention as an antidepressant agent, demonstrating promising results as well as having anti-suicidal properties. Esketamine nasal plus an oral antidepressants have demonstrated a statistically significant or clinically meaningful reduction in depressive and showed improvement in measures of depressive symptoms and other effi.. Read More»